A Case-control Study Adds a New Piece to the Aluminium/Breast Cancer Puzzle

Breast cancer (BC) is a heterogeneous group of human neoplasias in which age, family history of BC and hormone exposure are well-established risk factors.

Epidemiological data indicate that environmental factors largely contribute to BC incidence. For instance, migrants from eastern Asia, where the BC incidence is generally lower than in Western populations, develop the same rate of BC as the Americans, after having moved to the USA (Key et al., 2001). In addition, specific BRCA mutations lead to BC earlier in life in patients born after 1940, compared to those born before that year (King et al., 2003).

Much remains to be understood regarding the identity and relative contributions of environmental factors to breast cancer incidence.